Vertebral artery plaque is the formation of redundant organisms on the inner wall of bilateral vertebral artery vessels, which is a localized manifestation of systemic atherosclerosis, and is relatively rare compared to carotid artery plaque. Early vertebral artery plaques can be controlled by dietary adjustments, appropriate exercise, smoking and alcohol cessation, and control of blood pressure, blood lipids and blood glucose to control the further formation of plaques. Some patients can also stabilize plaque by taking oral statins, such as atorvastatin. When the plaque reaches the middle stage, close dynamic observation should be carried out and lipid-lowering and antiplatelet therapy should be strengthened. Commonly used antiplatelet drugs include aspirin and clopidogrel tablets, and the side effects of the drugs need to be noted. When vertebral artery plaque reaches the middle or late stage, it can cause severe vascular stenosis, which in turn leads to symptoms such as dizziness, headache, transient blackout and even fainting. At this point, timely medical attention is needed for treatment such as intervention or endarterectomy. When vertebral artery plaque is detected, it is recommended that patients go to the hospital in a timely manner, under the guidance of specialists, so as to avoid delaying the condition.