At present, Jiaotai Pill has no clear side effects. Jiaotai Pill has the effect of transportation of the heart and kidneys, and is mainly used for the treatment of palpitation and insomnia caused by the lack of communication between the heart and kidneys, and sores on the mouth and tongue caused by the hyperactivity of the heart fire. Jiaotai Pill is composed of two traditional Chinese medicines, Huanglian and Cinnamon, which is a representative prescription for the transportation of the heart and kidneys (the heart fire descends and the kidney water rises to restrain each other). Clinically, it can be used to treat heart palpitations (rapid heartbeat, often accompanied by panic), insomnia, nocturnal restlessness, and mouth and tongue sores caused by excessive heart fire, etc. caused by heart-kidney dissonance (heart fire is strong, kidney yin is weak, and the physiological functions of the heart and kidneys are imbalanced). The drug composition of Jiaotai Pill is very simple, in which Huanglian has the effect of clearing the heart and lowering fire to get rid of vexation, while Cinnamon has the effect of inhibiting the upward inflammation of fire evil of the kidneys, and at the same time inhibiting the effect of Huanglian’s bitter cold. The combination of the two medicines can make the heart fire descend, the kidney yang recover, the kidney water bear, and the heart and kidney intermingle. The side effects of Jiaotai Pills are still unknown, patients should use Jiaotai Pills correctly under the guidance of professional Chinese medicine practitioners.