Parkinson’s or dementia, dumb and dumber

In daily life, people often do not distinguish Parkinson’s disease from dementia, and most people have the idea that Parkinson’s disease is not the same kind of dementia. Patients are also troubled by the fact that they are obviously suffering from Parkinson’s, but how come the more they look like Alzheimer’s? Many people who are worried about their parents’ condition say that they are “confused” between Parkinson’s and dementia. Although Parkinson’s disease and Alzheimer’s disease both occur in old age, there are significant differences between Parkinson’s disease and dementia in terms of clinical manifestations, pathogenesis, and treatment methods. At the same time, because Parkinson’s disease and Alzheimer’s disease are both diseases of the elderly, they are usually classified as “degenerative diseases” of the nervous system, i.e., diseases in which certain parts of the brain and certain types of neurons (brain cells) appear to be significantly dead. Therefore, there is a close relationship between the two. Parkinson’s and dementia are not two separate diseases, and even older patients with Parkinson’s disease have a 78% chance of finding dementia within 8 years. Hospital neurologist Professor Wang pointed out that the onset and development of cognitive dysfunction in Parkinson’s disease are insidious, and if detected early can intervene in the use of medication, and appropriate supplementary activities can also slow the progression of dementia. Parkinson’s aggravation? Parkinson’s disease and dementia are not two separate diseases. First, 30% to 40% of Parkinson’s disease patients overall suffer from cognitive impairment or even dementia, and epidemiological surveys have found that 16% of first-time Parkinson’s disease patients already have cognitive decline, and about 10% of Parkinson’s disease patients progress to Parkinson’s dementia each year, with older Parkinson’s disease patients having a 78% chance of finding dementia within 8 years. Patients with dementia, meanwhile, can also develop Parkinson’s-like symptoms such as tremors, stiffness, slow movements, and gait disturbances in later stages. Parkinson’s disease dementia needs more attention. If you mistake the inability to use household appliances normally, the inability to finish stir-frying and cooking alone, memory loss, and the inability to express your feelings as just an aggravation of Parkinson’s disease, you will miss the time to treat it. Teach you to distinguish Parkinson’s disease dementia from Alzheimer’s disease 1. With this type of dementia, there is a decline in executive ability, attention, memory, language ability, visual-spatial ability, and changes in emotional behavior. For example, there is no way to organize, plan, or complete an activity; there is no way to cook a hearty meal; there is no way to manipulate more sophisticated equipment; there is no way to concentrate on one thing; there is no way to complete two consecutive actions; there is a decrease in alertness; attention spikes and decreases; talking to people is always a bit of an answer, like pulling things together; there is no way to immediately remember what you just did/happened; it is easy to forget faces or things What shape, poor spatial memory; do not like to initiate speech, speak with lower volume and pitch, also not fluent; perception of seeing things, orientation deviation, may fall more easily. Emotional and behavioral changes may include “delusions” such as seeing snakes, ghosts, tigers, and other distinctive things in their rooms; accusing family members or babysitters of trying to hurt them, who stole their money, or even suspecting their partners of being unfaithful to them. They may experience severe depression, anxiety, apathy, etc., and are easily provoked or even manic. 2, Alzheimer’s disease That is, the dementia that has been popularized in the past two years by the medical proper name of Alzheimer’s disease, is better recognized because it is characterized by memory impairment. For example, aphasia, loss of use, loss of reading, loss of recognition; indifference, irritability, lack of active activity; and Parkinson’s-like symptoms such as trembling, stiffness, and slow movement may appear in advanced stages. Compared to Parkinson’s disease dementia, Alzheimer’s disease has less attention and executive impairment, and because of information storage impairment, memory loss cannot be answered accurately even after prompting. It should be reminded that the chance of progressing to Alzheimer’s disease with Parkinson’s disease is four to six times higher than that of the general population! Parkinson’s dementia requires discontinuation of anticholinergic drugs. As many Parkinson’s patients and their families know, the gold standard of medication for Parkinson’s disease is compounded levodopa, with six commonly used drugs. And once a diagnosis of Parkinson’s dementia is confirmed, drug use needs to be adjusted. The first principle in the treatment of Parkinson’s disease dementia is to discontinue anticholinergic drugs such as Antan and amantadine, and to administer cholinesterase inhibitor therapy early; secondly, if patients develop visual hallucinations and other psychiatric symptoms, consideration should be given to sequentially reducing or discontinuing Antan, amantadine dopamine agonists and monoamine oxidase inhibitors; if there is no improvement in symptoms, levodopa should be considered for gradual reduction; if the above measures are still taken If symptoms or extrapyramidal symptoms worsen despite the above measures, it is advisable to choose non-classical antipsychotic drugs with definite efficacy and small extrapyramidal adverse system. It is advisable to start with small doses and slowly increase them to therapeutic doses. In addition to pharmacological treatment, cognitive rehabilitation is also important for Parkinson’s patients with cognitive impairment. First, visual memory, map work, color block arrangement, arranging numbers, item classification and other memory aids, computer-aided training software, etc. can be targeted, and a variety of rehabilitation training methods can improve cognitive function in a short period of time. Second, motor rehabilitation can be conducted. Research in the New England Journal of Medicine, an international authoritative journal, shows that regular tai chi can better improve the balance function of Parkinson’s disease patients, reduce falls and improve the prognosis; brisk walking for 150 minutes per week can help slow down the degree of cognitive decline; swimming, which has been written into the exercise rehabilitation guidelines for Parkinson’s disease patients. In addition, dance and music therapy are also viable adjuncts to treatment.