The cause of pain at the junction of the thigh and lumbar region is usually due to pear-shaped muscle syndrome and epiglottic neuritis. In clinical practice, pear-shaped muscle syndrome is the main cause of pain in this area. Pear-shaped muscle syndrome mainly compresses the sciatic nerve, resulting in a jamming of the sciatic nerve at the outlet, causing local pain symptoms, and in severe cases, causing lower limb pain, muscle atrophy, numbness, and weakness. Mild pear-shaped muscle syndrome can be relieved by medication and local physical therapy. Medications such as Futalin tablets, Yunnan Baiyao capsules, Lumbar pain capsules, and methylcobalamin tablets can provide significant relief of local symptoms. For patients whose lower limb activities are limited and affect walking, local closure therapy, such as local injection of tretinoin, can relieve local edema and relieve local pain symptoms. When the local adhesions are heavy, local release treatment can be performed to relieve the symptoms.