Atractylodes macrocephala is used symptomatically in the treatment of constipation is not harmful. Atractylodes macrocephala has the effect of tonifying the qi and strengthening the spleen, and is effective in treating constipation due to qi deficiency. Atractylodes macrocephala is used to treat Yin deficiency constipation, heat constipation, Yang deficiency constipation and other types of constipation is harmful, sometimes lead to the aggravation of constipation, is not conducive to the recovery of the condition. During the taking of Atractylodes macrocephala, it should not be used with peaches, plums, bird meat, coriander, garlic, mackerel, and should not be used with the sympathetic mediator epinephrine. There is a hypoglycemic effect, hypoglycemic patients should not take a single drug in large quantities for a long time. Fetal restlessness in pregnancy is a heat evidence should not be single medicine large quantities. Where the external wind-heat or warm heat, solid heat within the blaze, yin deficiency fire (Yin essence deficit in the body, the emergence of hyperactive fire), blood deficiency and blood heat and other certificates should not be a single drug taken in large quantities. Long-term use of the disadvantages of injury to the fluid consumption, where the evidence of gastric yin insufficiency (deficiency of yin fluid in the stomach), fluid deficit, constipation, Yin deficiency, internal heat, a single drug is prohibited to take a large number of people. Long-term use has the disadvantage of congestion of qi, where there is evidence of qi blockage should not be a single medicine for long-term use. It is recommended to take atractylodes macrocephala for constipation under the guidance of a doctor in order to avoid adverse reactions or delay in the treatment of the disease.