(1) The primary focus is large and it is estimated that direct surgery is difficult. (2) The tumor grows rapidly and grows significantly within a short period of time. (3) The primary foci have obvious skin edema or pectoral muscle adhesions. (4) Those with large axillary lymph nodes or obvious adhesions with skin and surrounding tissues. (5) Cases with unsatisfactory tumor regression by preoperative chemotherapy. (6) Patients with inflammatory breast cancer who are striving for surgical resection.