Abnormal ST-segment changes are a vectorial change on the electrocardiogram, often due to inadequate myocardial blood supply or weak myocardial contraction, and are a sign of cardiac decompensation on the electrocardiogram. Cardiogenic diseases such as coronary artery disease, unstable angina, arrhythmia, myocarditis, pericarditis, and hypertrophic obstructive heart disease all have abnormal ST-segment changes. In addition, non-cardiogenic factors such as endocrine metabolic disorders such as hyperthyroidism, adrenocortical dysfunction or hypokalemia, hyponatremia plasma disorders, shock due to surgical infection, trauma, or hyperthermia may show abnormal ST-segment changes on the ECG.