Indications: (I) Acne, rosacea: moderate to severe acne, especially cystic acne, nodular acne and all kinds of intractable acne. (B) Condyloma acuminatum: (especially recurrent condyloma acuminatum), flat warts, common warts and so on. (C) Skin tumors: basal cell carcinoma, Bowen’s disease, squamous cell carcinoma, paget’s disease (eczema-like carcinoma) and so on. (D) Pre-cancerous lesions: solar keratosis, erythema accreta, mucous membrane leukoplakia, Bowen’s papulosis, etc.