Immunohistochemistry is usually not needed after a colposcopy biopsy if no heterogeneous cells are found, and further immunohistochemistry is needed if heterogeneous growths are present in the biopsy to make an accurate diagnosis. The decision of whether a colposcopy biopsy needs immunohistochemistry is made by the condition. Colposcopy is used to detect lesions in the cervix. If the colposcopy biopsy does not show any heterogeneous growths, further immunohistochemistry is usually not needed. If the colposcopic biopsy reveals heterogeneous cells, a high-grade lesion may have occurred, and further immunohistochemistry should be performed to confirm the diagnosis, to more accurately define the substance of the lesion, and to facilitate the treatment of the cause.