Atractylodes macrocephala is a very common Chinese herb with its own fragrance, mainly because it contains a lot of volatile oils. With the improvement of detection technology and the optimization of extraction process, more than 100 kinds of components can be isolated from the volatile oil of Atractylodes macrocephala. Many studies have shown that atractylone has the highest content in the volatile oil of Atractylodes macrocephala, reaching 60%-70%, which is one of the main active ingredients of Atractylodes macrocephala, followed by alkenes, which together constitute the multiple effects of Atractylodes macrocephala. The medicinal value of Atractylodes macrocephala is very high, especially its good effect on removing spots. However, Atractylodes macrocephala also has certain side effects and should be used with caution by people with easily allergic skin to prevent allergic symptoms. When Atractylodes Macrocephala is used for blemish treatment, it is mostly made of vinegar, which is acidic and can produce certain stimulation to the skin. Long-term use or skin soaked in vinegar for too long will cause skin breakage, making the skin appear dead skin, molting phenomenon, and in serious cases, dermatitis symptoms may also appear. In addition, the plant components contained in Atractylodes macrocephala are complex and diverse, and some people will have allergic reactions to Atractylodes macrocephala, which may cause red rash symptoms when removing spots or using Atractylodes macrocephala masks.