Vitamin C and amoxicillin can be taken together. However, the medication needs to be taken under the guidance of a medical professional. Vitamin C is not suitable to be taken at the same time with anticoagulant drugs, which may interfere with the anticoagulant effect. And amoxicillin is mainly avoided in combination with probenecid, tetracyclines, allopurinol, etc., which may lead to an increase in the blood concentration of amoxicillin, interfere with the bactericidal effect of amoxicillin, or present allergic skin reactions. Vitamin C and amoxicillin do not interact and can be taken together. Vitamin C is contraindicated in people who are allergic to vitamin C. Vitamin C is not suitable for long-term use, and symptoms of scurvy may occur with abrupt discontinuation of the drug after long-term use. Vitamin C can pass through the placenta and secreted into the breast milk, pregnant women take too much, can induce the newborn to produce scurvy, in the drug should be suspended breastfeeding. Amoxicillin is contraindicated in people who are allergic to penicillin, cephalosporins and carbapenems. The most common adverse reactions are diarrhea, nausea and the appearance of skin rashes; although there is no absolute conflict between the two, the medication can be taken at certain intervals. And both medications need to be used as prescribed under a doctor’s diagnosis.