Hepatobiliary diseases, a series of common chronic diseases involving the liver and biliary tract, mainly include viral hepatitis, cirrhosis, hepatocellular carcinoma, cholelithiasis, bile duct cancer, and gallbladder cancer. Hepatobiliary diseases seriously threaten people’s quality of life with their high morbidity and mortality. The liver is the largest glandular organ in the body, and the metabolism of sugar, protein, fat and many vitamins in food requires the participation of the liver; the biliary system has the function of secreting, storing, concentrating and transporting bile, which can emulsify fat and assist in the absorption of fat and fat-soluble vitamins. Changes in nutrient metabolism in patients with hepatobiliary diseases are mainly manifested in the impaired digestion and absorption of fats and fat-soluble vitamins and the negative nitrogen balance of proteins, which often cause malnutrition in the body. Patients with hepatobiliary diseases have disorders of lipid metabolism in the liver due to impaired liver function, reduced bile secretion, obstructed bile drainage in the liver, and reduced synthesis of triglycerides, phospholipids and cholesterol. Weakened hepatic degradation of cholesterol and reduced bile acid production weaken the role of bile acid in emulsifying fat, thus affecting the digestion and absorption of fat and fat-soluble vitamins. When liver damage or bile duct obstruction occurs, patients often suffer from abdominal pain, abdominal distension, fever, nausea and vomiting, causing a decrease in appetite and eating. The patient’s digestive and absorption functions are disturbed, the liver glycogen reserves are reduced and the energy supply is insufficient, which eventually leads to malnutrition. An important function of liver cells is to synthesize and secrete plasma proteins. When liver dysfunction occurs, protein metabolism is highly catabolic and metabolic, leaving the body’s protein metabolism in a negative equilibrium. The liver is the only factory that can handle all amino acids. In liver dysfunction such as cirrhosis, amino acid metabolism is abnormal, and the activity of branched-chain amino acid decarboxylase in the liver decreases, so that branched-chain amino acids cannot be decarboxylated in the liver and can only be decomposed and consumed in peripheral tissues through transamination, which seriously affects the physiological function of the body and leads to a series of malnutrition symptoms. Second, liver and gallbladder disease patients eight discipline 1, prohibit alcohol: alcohol in the nitrosamines can make liver lipid degeneration and carcinogenesis, hepatitis patients should not drip alcohol. 2, prohibit cold: liver disease patients with a weak spleen and stomach, cold food can cause gastrointestinal discomfort, can cause enteritis, protein loss with diarrhea, ascites and increased abdominal water. 3, prohibit greasy, eggs, soy products: the vast majority of patients with cirrhosis have secondary changes in the gallbladder wall, greasy, eggs, soy products hinder the excretion of bile, over-eating such food will appear rib pain, bloating, belching aggravated symptoms, should be eaten as little as possible. 4, prohibit the consumption of animal offal: animal offal is high in cholesterol, a large intake will increase the burden on the liver, liver disease patients should not eat more animal liver. 5, less salt limit salt: patients with liver ascites, salt should be fried before putting into various foods, eat as little as possible, because salt will slow down the abdominal fluid receding. 6, prohibit the abuse of tonic: dietary balance is the basic condition of health, improper tonic will cause recurrent disease. 7, prohibit the abuse of chemical drugs: chemical drugs have damage to the liver and stomach, hepatitis patients must be under the guidance of the doctor reasonable use of drugs. 8, prohibit smoking: tobacco contains a variety of harmful substances, which can damage liver function. Understand the liver and gallbladder disease on the absorption of human nutrition obstruction, in order to better prevention and treatment of liver and gallbladder diseases.