Whether urinary occult blood negative and urinary protein + is kidney disease mainly depends on the cause of urinary protein. If proteinuria is caused by physiological factors such as strenuous exercise, it is not a kidney disease; proteinuria caused by pathologic factors such as kidney stones and urinary tract infections is not considered a kidney disease, such as proteinuria caused by glomerulonephritis and nephrotic syndrome, it is a kidney disease. Physiological proteinuria may be related to strenuous exercise, fever, mental stress, change of body position, drug effects, etc. Usually, it can be improved after adjusting one’s own living habits or mentality, without special treatment, and it is not a kidney disease at this time. Pathological proteinuria can be caused by a number of disease factors, kidney stones, urinary tract infections and other causes of proteinuria is not considered nephropathy; such as glomerulonephritis, nephrotic syndrome, diabetic nephropathy, renal tubular interstitial disease and so on, at this time for kidney disease. If the patient found abnormal urine test, it is recommended to go to the regular hospital in time, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.