Gastrointestinal stone is a very common disease in daily life and medical clinic, this disease is caused by the patient due to the intake of food that can easily cause stones, of course, the symptoms of this disease in the clinic due to the degree of the disease and the performance of the different, which requires us in the prevention and examination of this disease, we must be careful examination and diagnosis, to avoid misdiagnosis or found not timely, causing more serious harm to the patient. This requires that when we prevent and examine this disease, we must carefully examine and diagnose it to avoid misdiagnosis or untimely detection, which may cause more serious harm to the patients. Diagnostic examination Patients with history of eating persimmons, hawthorn, black dates, and gastric symptoms soon after eating, including recurrent epigastric pain, vomiting, black stools, etc., should be alerted to gastric stone, which can be diagnosed by gastroscopy and X-ray examination. Laboratory tests: some patients may present with microcytic hypochromic anemia. Fecal occult blood test is positive in some patients, and persimmon skin-like material can be seen at the initial stage. Gastric fluid analysis shows increased gastric free acid compared to normal. X-ray examination: 1. X-ray barium meal fluoroscopy or gas-barium double contrast can find that barium produces shunt phenomenon in the stomach and shows free, lumpy, round or oval filling defect area floating on the upper layer of barium, while the structure of gastric mucous membrane is smooth and the wall of the stomach is soft. When the barium is emptied from the stomach, the mass shadow can still be seen with streaks, meshes, or sheets of barium adhering to it. There is no obvious pressure pain when pressing the mass shadow, and the shape and position of the outline can be changed with the strength, suggesting that the mass has a certain degree of compression and wandering. 2. Fiberoptic endoscopy can be used to observe the morphology and character of gastric stones directly under fiberoptic endoscopy. Vegetable gastrolith due to the different composition of the lump, can be yellow, brown, brown or green, often round, oval single or multiple free clusters. Gross gastroliths are usually black or tan, “J”-shaped or kidney-shaped, and can fill the body of the stomach or extend into the duodenum. Fiberoptic endoscopy can also find out whether the stomach is combined with gastritis, ulcer disease and other signs, if necessary, can also be clamped for analysis of the composition of the mass or complications of the stomach tissue. Therefore, suspected gastrolithiasis should be fiberoptic endoscopy as the first choice of diagnostic means. 3. Ultrasound ultrasound is helpful in the diagnosis of gastric stone. Usually the patient is instructed to drink 500 to 1000ml of water, sitting or semi-recumbent position examination, you can see the stomach has a clear boundaries of the image of the strong echogenic mass, floating in the upper layer of water, and can be changed with the position changes or peristalsis of the stomach and change position. Diagnosis Gastrointestinal stones 1.Functional dyspepsia usually has dyspepsia syndrome, such as acid reflux, belching, nausea, epigastric fullness and discomfort, but the gastroscopy and barium meal examination mostly have no positive findings, which is functional. 2. Chronic gastritis is characterized by chronic irregular epigastric pain, which can be identified by gastroscopy, and is mostly indicative of chronic gastro-sinusitis. 3. Gastrinoma, also known as Zuo-Ai syndrome, is caused by pancreatic δ-cell secretion of large amounts of gastrin. Diagnostic points are: ① BAO>15mmol/h, BAO/MAO>0.6; ② X-ray shows atypical location of ulcers, especially multiple ulcers; ③ refractory ulcers, easy to recur; ④ with diarrhea; ⑤ increased serum gastrin>200pg/ml (often>500pg/ml). 4. The differential diagnosis with malignant gastric ulcer or gastric cancer is gastroscopy with biopsy and barium meal examination; biopsy is required during gastroscopy to clarify the benign or malignant nature. 5. Gastric mucosal prolapse is intermittent epigastric pain, which cannot be relieved by acid suppressants and may be relieved by changing position such as lying on the left side. Gastroscopy and barium meal can be used to identify it, and X-ray barium meal can show the shadow of “muscarinic” or “parachute-like” defect in the duodenal bulb. We have learned from the above that the symptoms of gastrointestinal stones are diverse, which to a certain extent creates a lot of obstacles to our prevention and treatment work, but in order to ensure a healthy body, we must take active measures to resist the occurrence of this disease. In our preventive work, we should pay attention to exercise, maintain a balanced diet, pay attention to eating habits, and try not to consume foods that are prone to cause stones.