Toe gout stone dissolution methods mainly use uric acid-lowering drugs, need to be based on the patient’s specific condition, personal constitution and other factors for the choice of treatment program. Gout stone is gout patients urate deposition in the auricle, Achilles tendon, bursa, eagle’s head and other parts of the formation of nodules, often grayish-white or white paste, tofu dregs-like material, can be surgical methods to remove the larger gout stone, but this method can not be a radical cure for gout stone, long-term control of the dissolution of the gout stone still need to rely on drug therapy. Gout stone patients need to take alkalizing urine and lower uric acid drugs for treatment of dissolved gout stone, which alkalizing urine helps patients with urate excretion and dissolution, and benzbromarone, febuxostat, allopurinol and other uric acid-lowering drugs can reduce the patient’s body uric acid level in order to control the gout stone continues to form. Drugs need to be used under the guidance of a physician, it is recommended that gout stone patients to the rheumatology and immunology department of a regular hospital for detailed consultation, to avoid self medication.