The overall probability of malignancy is higher for pure ground glass nodules, at about 18%. The risk of nodule malignancy is also related to nodule size and morphology. Lung nodules can be categorized according to their density into solid nodules, pure ground-glass nodules, and mixed nodules with both solid and ground-glass components. Among them, solid nodules have the lowest risk of malignancy, mixed nodules have the highest probability of malignancy, and pure ground-glass nodules have a higher probability of malignancy, about 18%. The probability of malignancy of pure ground glass nodules is related to nodule size, morphology, patient age, gender, and family history, and needs to be analyzed specifically on an individual basis. If the Brock model is used for prediction, the risk of malignancy is assessed according to the patient’s sex, age, presence of family history of lung cancer, presence of emphysema, and nodule type, size, location, number, and presence of burr sign. A probability of malignancy of less than 10% is considered a low malignant risk and can be followed up with repeat CT. a probability of malignancy of greater than 10% is considered a high malignant risk and treatment such as puncture biopsy or surgical resection is generally recommended. When pure ground glass nodules are found, patients are advised to go to regular hospitals in time and listen to the advice of specialized doctors.