Oral fibrosis is not necessarily cancerous and is a benign lesion. However, if the mucosa develops to a certain extent over a long period of time, it also has the possibility of becoming cancerous. Oral fibrosis is mainly related to betel nut chewing, and it occurs mostly in women over 40 years old, with common sites such as the palate and cheeks. It mainly shows white lesions, which gradually develop into fibrous cords under the mucosa. Microscopically, fibrous degeneration occurs in the lamina propria and submucosa of the mucosa, collagen fiber disorders presenting vitreous degeneration, as well as vascular stenosis, etc. At the same time, different degrees of inflammatory cell infiltration also occurs. It is recommended to develop good dietary habits and try not to chew betel nut. Also avoid the stimulation of adverse factors to prevent the disease from occurring.