The elimination of non-lactating acute mastitis lumps includes oral antibiotics, localized warm compresses, and surgical incision to drain the abscess. 1. Oral antibiotics: Acute mastitis is a suppurative inflammation caused by bacterial infection, which can be treated with oral antibiotics, common drugs include amoxicillin and ceftazidime. 2. Localized hot compresses: localized hot compresses can help promote blood circulation and the absorption of lumps, which is an auxiliary means of treating acute mastitis. 3. Surgical incision and drainage: If conservative treatment is ineffective and the lump does not subside and leads to the formation of a breast abscess, a surgical incision is needed to drain the pus. The use of medication should be under the guidance of a physician, if the symptoms are not significantly relieved or worsened after the use of medication, you should promptly go to the local regular hospital.