Prostate MRI is normal, whether to perform puncture should be combined with the specific situation, some cases still need to do further puncture biopsy. 1. No need for puncture: If the prostate is normal through rectal examination, tumor markers such as prostate-specific antigen levels have not risen, and there is no obvious discomfort, and at the same time, the results of prostate MRI are normal, usually there is no need for puncture biopsy, and regular observation will be sufficient. 2. Need for puncture: If the prostate MRI is normal, but there is hematuria, hard nodules on rectal examination, and prostate-specific antigen is obviously rising, prostate cancer cannot be ruled out, and it is recommended to perform a puncture biopsy in this case. In this case, it is recommended to perform a puncture biopsy. Clinically obvious symptoms of elevated prostate-specific antigen, accompanied by hematuria, need to be promptly admitted to the hospital to consult a doctor for examination, and to carry out standardized treatment under the guidance of the clinician after diagnosis of the disease, so as to avoid delays in the condition.