The generic name of the diaphragm is nonoxynil suppository, and women use nonoxynil suppository for better contraceptive effect. However, it is important to note that they should not be removed immediately after intercourse, or the contraceptive effect may be affected. As a kind of external contraceptive pill, nonoxynol ether suppository is put into the vagina five minutes before coitus, and after dissolving, it can interact with sperms, thus avoiding the combination of sperms and egg cells and achieving contraceptive effect. However, it should be noted that the use of nonoxynol ether suppositories should be avoided immediately after intercourse, otherwise the contraceptive effect may be reduced. Care should be taken when using nonoxynol ether suppositories to place them deep into the vagina, otherwise the contraceptive effect may also be compromised. Women with suspected vaginal tumors should be prohibited from using nonsteroidal pessaries. The use of nonoxynol ether suppositories may lead to local allergies and other adverse reactions, and should be used under the supervision of a physician.