It is not recommended to give ibuprofen to children on an empty stomach, ibuprofen has an irritating effect on the gastrointestinal tract, and children’s intestines and stomachs are not yet mature, so they are prone to gastrointestinal reactions. Ibuprofen is a commonly used antipyretic, analgesic and anti-inflammatory drug in daily life, commonly used in infants and young children to reduce fever, relieve mild headache, sore throat and toothache caused by colds and flu. It is contraindicated in patients who are allergic to non-steroidal anti-inflammatory drugs, those with active peptic ulcers or those with previous recurrent ulcer bleeding, gastrointestinal bleeding or perforation. Common adverse reactions include gastrointestinal reactions such as nausea, vomiting and diarrhea. Children with immature gastrointestinal development may experience increased adverse reactions when taken on an empty stomach. If you need to give ibuprofen to your baby, it is recommended that you take it under the supervision of a doctor, and it is recommended that you take it with a meal.