There is no such thing as the best treatment for endometrial hyperplasia simplex. Patients can improve their symptoms through medication and surgery. 1. Medication: Patients with simple endometrial hyperplasia can take oral progestins such as dydrogesterone, micronized progesterone, medroxyprogesterone acetate, etc., or oral estrogens such as estradiol valerate and estradiol benzoate under the guidance of a doctor. Some patients can also take oral contraceptives, such as deoxyprogesterone, ethinyl estradiol, progesterone, compound cyproterone acetate, and so on. Most of the patients can stop bleeding after drug treatment. 2. Surgical treatment: If patients can’t relieve the symptoms of the disease by simply using medication, or if abnormal uterine bleeding persists, they need to take surgical treatment in time. Such as scraping the uterus, so as to quickly stop bleeding. Or endometrial removal, hysterectomy and so on. Once diagnosed with endometrial hyperplasia simplex, patients need to actively cooperate with doctors to take relevant treatment measures.