Benign prostatic hyperplasia has now become a common and frequent disease that seriously affects the quality of life of older men. Patients can usually be relieved with medication, but for cases where medication is ineffective and accompanied by serious complications, surgical treatment is the most thorough. In the last decade, intracavitary minimally invasive has gradually replaced the old open surgery as the mainstay of surgical treatment of BPH. ”The Holmium laser prostate enucleation is the brightest star of the various intra-cavity minimally invasive surgical treatments in recent years. It is the best way to get the most out of your life. The Holmium laser prostate enucleation has been used clinically in top foreign medical institutions and is recognized by foreign experts as a new minimally invasive treatment method that is expected to replace the current traditional transurethral resection of the prostate, but there are few hospitals in China that carry out this technology. The Holmium laser has the ability to cut precisely, and the principle is to emit a more powerful laser beam than high-frequency current and ordinary laser power, by 0.5 mm optical fiber, through the natural urethral lumen to the prostate area, like peeling an orange, the hyperplastic gland from the prostate envelope intact, and then use the intra-cavity tissue crusher to peel the prostate from the large to small, from the urethra suction out of the body, the whole process under the monitor. The whole procedure is performed under a monitor. The procedure is performed under the monitor. Unlike traditional surgery, which is more traumatic, this technique has a minimal impact on the patient’s body, especially for large prostates, elderly patients or patients with other combined systemic diseases, showing its effectiveness and safety. It is worth mentioning that for some patients with BPH with bladder stones or urethral strictures, only one inpatient anesthesia is needed to solve both diseases, thus “killing two birds with one stone”. At present, the Department of Urology of the Ninth People’s Hospital of Shanghai Jiaotong University School of Medicine took the lead in introducing the most advanced high power U100+ holmium laser from the United States two years ago and completed the research of holmium laser prostate enucleation, which has broken through several technical difficulties and mastered the key points of complete prostate enucleation technology, and successfully used it for the treatment of prostate hyperplasia. The laser enucleation is superior to traditional open prostate enucleation and transurethral electrodesiccation of the prostate, with fewer complications, shorter average post-operative indwelling urinary catheterization time, shorter hospitalization days, and faster recovery of patients.