The swollen and itchy foreskin may be caused by bacterial infection, fungal infection, allergic factors, with different triggers and different medications, including cefdinir, itraconazole, cetirizine and so on. 1. Bacterial infection: For the swollen and itchy foreskin caused by bacterial infection, it can be treated with antibiotic drugs such as cefdinir and ciprofloxacin orally, and it can also be treated with topical erythromycin ointment, mupirocin ointment and other drugs. 2. Fungal infection: then there are fungal infections, should be oral antifungal drugs for treatment, such as itraconazole, and with the use of some topical antifungal drugs, such as clotrimazole ointment, terbinafine ointment and so on. 3. Allergic factors: for allergic factors caused by the itching and swelling of the foreskin, can be used externally with glycerine lotion, tacrolimus ointment and other drugs for treatment, and in severe cases must be taken orally antihistamine drugs, such as cetirizine and loratadine. There may be other reasons for the swelling and itching of the foreskin, so it is recommended to consult a doctor. In the process of treatment, we must listen to the doctor’s guidance, safe and reasonable use of medication, do not unauthorized use of drugs.