Clomiphene, also known as clomiphene citrate capsules, is an anti-sex hormone drug that stimulates the function of ovulation. This drug has a dual effect of weak agonism and strong antagonism to estrogen, which stimulates ovulation. Firstly, by interfering with the negative feedback of endogenous estrogen, it can increase the secretion of luteinizing hormone and folliculogenic hormone and stimulate the growth of follicles. After follicle maturation the release of estrogen increases, and through positive feedback the release of preovulatory gonadotropins is stimulated to peak, whereupon ovulation can occur. Clomiphene in clinical practice can be used mainly for the treatment of female infertility in the absence of ovulation, for patients with certain estrogen levels in the body. It can also be used to treat luteal insufficiency and to test the function of the ovaries. In addition, it can be used to detect abnormalities in the function of the hypothalamic-pituitary-gonadal axis in men, and it can also be used to treat male infertility due to too few sperm. In conclusion, clomiphene is an anti-sex hormone drug that promotes ovulation mainly by regulating the level of hormones in the body.