The management of long-term acne (medically known as acne) includes general care and medication to get rid of acne. 1. General care: Avoid a diet high in sugar and reduce the intake of spicy and irritating foods. Pay attention to facial cleanliness and hygiene, use mild cleanser to wash your face to minimize facial irritation. Pay attention to ensure sleep, avoid late night or labor. 2. Drug treatment: you can use topical retinoic acid drugs such as retinoic acid ointment, adapalene, etc.; or topical benzoyl peroxide, azelaic acid and other drugs, if necessary, oral antibiotic treatment, such as minocycline, doxycycline, etc.. When nodular cysts are the main manifestation, oral isotretinoin and other drugs are needed. It is recommended that patients diagnosed with acne, under the guidance of the doctor reasonable medication treatment, not blindly self-medication.