Diffuse thyroid lesion in women is a pathological state change. Clinically, the most common types of diffuse thyroid lesions are nodular goiter, thyroid cancer, Graves’ disease, etc. Prompt medical attention is recommended. 1. Nodular goiter: when the nodule is relatively large, it can compress the trachea, esophagus, blood vessels, nerves, etc., which may cause choking, discomfort when swallowing, facial edema, dilatation of superficial veins in the neck and upper chest, etc. 2. Thyroid cancer: the main symptoms of thyroid cancer are enlarged thyroid gland or nodules, difficulty in swallowing, difficulty in breathing, local pain, and distant metastasis in the later stage. Some patients also have diarrhea, palpitation, endocrine disorders, and in severe cases, severe dyspnea and suffocation. 3. Graves’ disease: manifested as hyperthyroidism, excessive secretion of thyroid hormones, resulting in high metabolism. Patients may have fear of heat, polyphagia, weight loss, muscle weakness; cumulative cardiovascular panic, palpitations; some patients will also have irritable bowel, diarrhea, hyperactivity; and even lead to women’s menstrual disorders, male sexual dysfunction. Female diffuse thyroid lesions to the hospital, must choose a regular hospital, under the guidance of a professional physician for regular treatment, is conducive to achieving better therapeutic results.