Clustered breast calcifications are not necessarily malignant tumors, but may also be benign lesions such as intraductal papillomas. Clustered breast calcifications are descriptions of the distribution of breast calcifications, and generally have to be combined with the morphology and density to determine the likelihood of benign or malignant breast calcifications. About 30~50% of clustered breast calcifications are malignant tumors such as breast cancer, which may be caused by necrotic fragments of cancer cells and secretion of cancer cells, but there is also a greater possibility that they are caused by benign lesions such as breast cysts, fibromas, intraductal papillomas, etc., which may be associated with active secretion of mammary cells and deposition of calcium salts. Breast cluster calcification should be removed in time, and then pathological examination should be done. If it is a malignant tumor, radical mastectomy should be performed, and chemotherapy, radiotherapy and endocrine therapy should be selected according to the pathological results. Breast cluster calcification is a common breast disease, need timely and detailed examination and treatment, can be treated by surgery, usually more adhere to the review.