Men who take norfloxacin can usually have children. Norfloxacin is a quinolone antimicrobial drug, absorbed rapidly after oral administration, about 1~2 hours blood concentration reaches the peak, can be widely effected in various tissues and body fluids of the body, such as the liver, kidneys, blood, urine, etc. The drug does not have much effect on the male reproductive system and sperm quality. Norfloxacin is a short-acting antibacterial drug, which can be metabolized quickly in the body, part of which is excreted from urine through glomerular filtration, and part of which is excreted from bile and feces through the hepatobiliary system, with a blood elimination half-life of 3 to 4 hours, which can be prolonged to 6 to 9 hours when men have renal hypofunction. Therefore, men taking norfloxacin can usually have children.