Toothache and face swelling should be alert to acute apical periodontitis and acute wisdom tooth pericoronitis and other diseases. 1. Acute apical periodontitis: mostly due to caries or other factors of stimulation, pulp infection, failure to timely and effective control, infection beyond the apical foramen, inflammation of the periapical tissues, teeth appear severe pain, can not be touched, the corresponding apical region and facial swelling, severe cases are accompanied by generalized low-grade fever, etc., and need to be promptly carried out in the open water drainage, relieve symptoms. 2. Acute wisdom teeth pericoronitis: is an inflammation that occurs in the soft tissues around the wisdom teeth, mostly due to wisdom teeth obstruction, localized food impaction, resulting in bacterial infection, can appear red, swelling, heat, pain and other inflammatory symptoms, facial swelling, limited mouth opening. Toothache face swelling, need to promptly seek medical attention, under the guidance of the doctor for examination and treatment to avoid delays in the condition.