The specific cause of difficulty in holding urine in women depends on the patient’s condition and is mainly determined by whether the patient is accompanied by other symptoms. For example, acute cystitis may cause severe urinary frequency, urinary urgency, and urinary pain, which may lead to difficulty in holding urine. Such patients should be actively treated with antibiotics to combat the infection, and their symptoms will improve significantly once the infection is controlled. In addition, some patients may have difficulty holding urine due to childbirth or surgery, which is also known as urinary incontinence, and in severe cases, these patients may even require surgery to achieve better results.