What causes migraines? This is very puzzling to many patients suffering from migraines. In a nutshell, there are several points. 1. Genetics is the main factor of migraine, we will find that many migraine patients’ parents or siblings also have migraine, and the probability of relatives getting migraine is three to six times of the general population; 2. As the saying goes, disease enters through the mouth, so special attention must be paid to what you eat in your belly. Cheese containing tyramine, meat containing nitrite antiseptic such as hot dogs or bacon, chocolate containing phenylethylamine, food additives such as monosodium glutamate (MSG), red wine, etc. can all induce migraine. Finally, mental factors, such as excessive stress and tension, can also cause nerve irritation and trigger migraine. Some of these factors can be avoided and some are unavoidable. All we can do is to make our best efforts to avoid them as much as possible in terms of diet and mental health. So what should we do if the migraine has developed to a serious stage and the effect achieved by medication is not very obvious? Does surgery work? This is the question in the minds of many patients. Currently, there is a very effective surgical procedure called microvascular decompression that has been proven to be effective in the treatment of migraines. With this procedure, the compression of the blood vessels on the nerves is released, so that they can resume a non-disturbing relationship with each other and no longer compress each other.