Painful touching of breasts is commonly caused by the following reasons: there are mastitis, fibroid, breast hyperplasia, breast trauma, cardiothoracic diseases, herpes zoster, breast cancer, and so on. 1. Mastitis: It occurs in breastfeeding women, and is related to milk stagnation and bacterial infection. The breast will be red and swollen, and the patient will feel pain when touching the breast at the place of inflammation. 2. Breast hyperplasia: After breast hyperplasia occurs, the breast will be painful, and a breast lump may be formed, which is often painful when touching the lump. 3. Breast injury: excessive squeezing of the breast can lead to breast injury and pain when touching the breast. It is recommended that the patient go to the hospital, can improve the relevant examination, such as ultrasound, combined with the physical examination of the breast, usually can clarify the cause.