Not working hands calluses, this situation may be the palm area of the abnormal keratinization, this abnormal keratinization may be palmoplantar keratosis, palmoplantar keratosis has a variety of factors lead to, some of them are due to genetic factors, such as hereditary symmetrical erythema keratosis, there may also be hereditary factors lead to punctate keratosis, regardless of which keratinization factors are formed, in the treatment of the main Perform antikeratosis treatment. Calluses may also be formed by other infections that occur in patients, such as fungal infections, which repeatedly stimulate the epidermal stratum corneum, resulting in hyperplasia and hypertrophy of the stratum corneum, and calluses may also appear. There may also be corns formed due to improper friction or extrusion of the area, whatever the case may be, it needs to be treated differently.