Compound Glycyrrhizin Tablets may cause an increase in creatinine and the drug is recommended to be used under medical supervision. Fufang Glycyrrhizin Tablet is mainly used for the treatment of chronic liver disease, which can improve the abnormal liver function. Short-term use of Cotrimoxazole has no adverse effect on the kidneys, but long-term use of Cotrimoxazole in large quantities may cause damage to the kidneys. Since Glycyrrhizin Complex is mainly excreted by the kidneys in the body, and finally excreted in the urine. Therefore, long-term use of Glycyrrhizin Compound in large quantities may lead to aggravation of edema, hypertension, etc., which may cause some damage to the kidneys, manifested by the increase of creatinine and hypokalemia. Adverse effects of taking compound glycyrrhizin tablets include hypokalemia, elevated blood pressure, sodium and fluid retention, swelling, decreased urine output, weight gain and other symptoms of pseudoaldosteronism, as well as weakness, myalgia, paresthesia of the limbs and other symptoms of rhabdomyolysis. Aldosteronism patients, myopathy patients, hypokalemia, end-stage cirrhosis patients are prohibited; pregnant women and lactation with caution. Compound glycyrrhizin tablets are recommended to be used under medical supervision, do not self-medicate.