Hepatitis B patients can have children when their condition is stabilized, if the mother is hepatitis B patient, the quantitative examination of hepatitis B DNA is needed during pregnancy, and if the viral load is high, oral tenofovir is needed to carry out mother-to-child blockage, and the child needs to be vaccinated with anti-hepatitis B virus immunoglobulin and hepatitis B vaccine at the first time after the child is born. Hepatitis B is a disease caused by infection of the body with the hepatitis B virus. Hepatitis B can be present in asymptomatic carriers or in patients with abnormal liver function. Hepatitis B does not usually affect men who want to have children, while women with hepatitis B need to take care of their health and wait until their condition is stable or stabilized before they can prepare for pregnancy. Mothers with hepatitis B may transmit hepatitis B virus to their children through placenta and birth canal during pregnancy and delivery, therefore, mothers need to check their viral load during pregnancy, and oral tenofovir is recommended to block the virus if the viral load is high. Newborns need to be vaccinated with anti-hepatitis B virus immune globulin and hepatitis B vaccine at the first time to neutralize the hepatitis B virus in the body and encourage the newborn to develop active immunity and produce hepatitis B antibody. Hepatitis B patients who have the need to have children should consult professional hepatologists in time and prepare for pregnancy, gestation and delivery under the guidance of hepatologists and obstetricians and gynecologists.