Cholinesterase is one of the liver function tests that reflects the functional status of the liver. Increased cholinesterase often indicates impaired liver function and can be seen in a variety of liver diseases, such as fatty liver, hepatitis B, or alcoholic cirrhosis. If degeneration or necrosis of liver cells occurs, there is often an increase in cholinesterase, which can be used as an indicator to monitor liver function. In addition, some other systemic diseases can also cause increased cholinesterase, such as hyperthyroidism, chronic renal failure, diabetes mellitus, and some neurological diseases can also cause high cholinesterase. If cholinesterase is high, it is important to follow up regularly to monitor the changes in indicators and find the cause.