The indications for antiviral therapy for chronic hepatitis B are as follows: 1. Antiviral therapy should be considered in cases where there is inflammatory activity in the liver and the inflammation does not return to normal after conventional liver-protective therapy and the virus has replicated. 2. Antiviral therapy should be considered in cases where liver ultrasound or liver hardness scan suggests the possibility of liver fibrosis formation and the virus has replicated, even if liver function is normal. 3.Even if the liver function and liver ultrasound are normal, but the liver biopsy indicates that the inflammation in the liver is above grade 2 or the fibrosis is above grade 2, as long as the virus has replication, antiviral treatment should be considered. 4.In the case that there is cirrhosis of the liver and the virus has replication, antiviral treatment should be considered.