The development of tiny lung nodules after vaccination with Neocoronavirus vaccine is less related to Neocoronavirus vaccine and is mainly considered to be caused by itself. The main components of the vaccine include inactivated and recombinant protein of Neocoronavirus, which mainly works in the blood system and generally does not cause lung nodules. The formation of lung nodules takes some time, and if lung nodules are found after vaccination and the time interval is relatively short, it can be basically ruled out that they are caused by the vaccine. The main consideration is that it may be caused by their own reasons, such as lung tissue fibrosis caused by lung infection, which can form lung nodules, past history of tuberculosis, which can appear old tuberculosis foci, lung cancer metastasis, which can also form lung nodules. Therefore, it is necessary to consult a doctor in time, combined with fiberoptic bronchoscopy and other examinations, to further clarify the nature of nodules and treatment.