Luteal hematoma can be treated with ciprofloxacin if it is large in combination with an infection. A corpus luteum hematoma is an abnormality that occurs during ovulation, when the outer layer of the follicle ruptures and causes the corpus luteum to bleed. If the corpus luteum hematoma is small, the body can slowly absorb it and there is no need to worry too much. However, if the corpus luteum hematoma is relatively large, it is necessary to carry out hemostatic treatment, observe the woman’s vital signs, and after the failure of conservative treatment, it is necessary to carry out surgical treatment. Some large corpus luteum hematoma will also be combined with infection, the need for anti-infection treatment, ciprofloxacin belongs to the quinolone antibiotics, gram-positive bacteria and gram-negative bacteria have a better antibacterial effect, if the corpus luteum hematoma is relatively large combined with infection, you can use ciprofloxacin. Ciprofloxacin can be used if the luteal hematoma is large and infected. The medication should be taken under the guidance of a doctor, and should not be taken without authorization in order to avoid adverse reactions.