Chronic sinusitis treatment drugs, need to be determined according to the specific symptoms, commonly used drugs are glucocorticoids, antibiotics, mucus drainage agents, intranasal decongestants and other drugs for treatment, it is recommended to follow the doctor’s instructions. 1. Glucocorticoid: common glucocorticoid nasal spray, such as fluticasone propionate, trimethoprim nasal spray, etc., the safety and tolerability of the drug is better, reduce nasal mucosal edema. 2. Antibiotics: commonly used drugs include amoxicillin and erythromycin, etc. Patients should choose appropriate antibiotics for anti-infection treatment according to the drug sensitivity results. 3. Mucus promoter: common drugs are eucalyptus pinocchio enteric soft capsule and so on. The drug can dilute respiratory mucus, improve cilia activity, promote nasal discharge, pay attention to gastrointestinal discomfort, allergies and other adverse reactions. 4. Intranasal decongestants: common drugs are hydroxymetazoline and so on. The drug can help nasal ventilation and drainage, mostly used in nasal congestion, pus and snot. Treatment usually lasts no more than 7 days. It is important to use the medication under the guidance of a doctor to avoid adverse consequences.