Triple-negative breast cancer is a pathologic type of breast cancer, and bone metastasis indicates that the patient is in the advanced stages of the disease and is experiencing skeletal metastases.
There is a relationship between the development of breast cancer and hormone levels such as estrogen and progesterone. When immunohistochemistry is performed, if the estrogen receptor (ER), progesterone receptor (PR), and proto-oncogene Her-2 are all negative, it is called triple-negative breast cancer. This type of breast cancer lesion is less sensitive to endocrine therapy as well as targeted drug therapy and therefore has a relatively poor prognosis.
Due to the invasive nature of breast cancer, metastasis usually does not occur in the early stage of the lesion and when the lesion is limited. When the lesion continues to develop, the cancer cells can metastasize to local tissues and distant organs through blood and lymphatic channels. Common metastatic organs of breast cancer patients are found in lungs, liver, bones, pleura, and so on.
Therefore, the occurrence of bone metastasis in patients with triple-negative breast cancer indicates that the condition is very serious and is already in the advanced stage of the disease, and regular treatment must be carried out under the guidance of doctors in order to prolong the survival time of patients as much as possible.