Patients with trigeminal neuralgia suffer from severe pain, so the patient’s body is more stimulated during the pain attack, resulting in a transient increase in blood pressure. However, if trigeminal neuralgia is treated in a timely manner, it will not cause hypertension when the pain is eliminated. If patients with trigeminal neuralgia do not undergo pain treatment, long-term, repeated pain can lead to mental stress, insomnia, anxiety and other emergencies, resulting in prolonged sympathetic excitation, leading to the sclerosis of blood vessels and the formation of hypertension. Therefore, patients with trigeminal neuralgia should be actively treated to prevent pain from causing a series of other complications.