Viral hepatitis is an infectious disease caused by a variety of hepatitis virus infections, resulting in inflammation or necrosis of the liver, there are five main types of hepatitis A, hepatitis B, hepatitis C, hepatitis D and hepatitis E. Among them, hepatitis A, hepatitis C, hepatitis D and hepatitis E are caused by RNA virus infections, while hepatitis B is caused by DNA virus infections, therefore, hepatitis virus DNA The reference value generally refers to hepatitis B. Hepatitis B virus DNA below 1000copies/ml is a normal value, and above 1000copies/ml means the virus is in active phase, and there is no specific upper limit value. The lower limit of hepatitis B virus DNA is even lower if tested with ultrasensitive reagents, such as 15 IU/ml or 20 IU/ml. The hepatitis B virus DNA value reflects the replication capacity of the hepatitis B virus and is an important indicator of whether the disease is effectively controlled and whether antiviral therapy is needed. Hepatitis DNA values below normal indicate that the virus is not replicating, i.e., the disease is normal or under effective control. If the hepatitis virus DNA value is higher than normal, the higher the value, the higher the viral replication and the stronger the infectiousness. At this time, laboratory and imaging tests should be performed to check whether clinical signs of hepatitis B, such as weakness, yellow urine, yellow skin staining, as well as abnormal liver function test results and liver fibrosis, are present, so as to determine whether antiviral treatment is needed. Clinically used antiviral treatment drugs include nucleotide analogues such as tenofovir disoproxil fumarate tablets and entecavir tablets, and interferon analogues such as pegylated interferon alpha-2a injection. In addition, in daily life, you should work and rest regularly, exercise appropriately, improve immunity, pay attention to the nutritional balance of diet, and review regularly.