Itchy clothes at night may be eczema, urticaria, scabies. 1. Eczema: the phenomenon of itching at night after taking off the clothes may be caused by eczema, the cause of its attack is complex, may be related to external stimuli, environmental changes, etc., there will be erythema, pimples, blisters and other lesions, usually accompanied by significant itching. 2. Urticaria: related to allergies, common triggers of allergies, including food, drugs, environment, physical stimuli, etc., there will be itchy sensation as well as the size of the wind, etc., and part of the population can be induced in a specific environment, so there may be nighttime undressing itchy body. 3. Scabies: it is a contagious skin disease caused by scabies mite parasites in the skin, due to the scabies mite is often active at night, therefore, the patient will appear at night after taking off the clothes all over the body itchy performance, in addition to finger cracks, scrotum, abdomen and other parts of the pimples, herpes papules, nodules and so on. There are many reasons for itchy clothes at night, so patients are advised to go to the hospital to clarify the cause of the disease.