Autoimmune hemolytic anemia in children is generally difficult to cure, but clinical remission can be achieved. 1. First-line treatment: despite the many adverse effects and high recurrence rate, adrenocorticotropic hormone is still the first choice for the vast majority of patients, through the use of adrenocorticotropic hormone, most patients can achieve clinical remission, but not a complete cure. 2. Second-line treatment (1) Splenectomy: patients with ineffective or intolerant adrenocorticotropic hormone therapy, ineffective high-dose hormone therapy, and children with frequent recurrent episodes of seizures need to undergo splenectomy. (2) Rituximab and other molecules: for refractory autoimmune hemolytic anemia that has failed to be treated with either of the above methods. If a child suffers from autoimmune hemolytic anemia, he or she must follow the doctor’s instructions for treatment, do not take medication or stop treatment without authorization, so as not to endanger the patient’s life.