Patient: autoimmune hemolytic anemia pregnancy In February 2008, I was hospitalized for dizziness and was tested for autoimmune hemolytic anemia. During the hospitalization, I took prednisone and azathioprine, and after I was discharged from the hospital, the dosage was slowly reduced, but the hemoglobin was unstable and the effect was not very obvious. In February 2011, I found out that I was pregnant and I wanted to have a baby, but after I got pregnant, I kept getting colds and my hemoglobin dropped again. The condition improved a bit, and now I am discharged from the hospital to recuperate at home. I wonder if autoimmune hemolytic anemia will affect the baby? Also, can autoimmune hemolytic anemia be cured? Is it better to have a cesarean section or a normal delivery in the future? Can the umbilical cord blood from my baby be used to treat autoimmune hemolytic anemia? Thank you for your help, doctor! Hematologist: Treatment of autoimmune hemolytic anemia in pregnancy Autoimmune hemolytic anemia is a disease caused by autoimmune disorder, which requires long-term medication and maintenance treatment. The effect of prednisone on the fetus is relatively smaller, and can be maintained by prednisone, and if necessary, by transfusion of washed red blood cells or red blood cell suspension. As long as the hemoglobin is normal, a normal delivery is possible and the decision on which method should be made by the obstetrician. Cord blood is not useful in treating your autoimmune hemolytic anemia. Patient: But I’ve read the instructions for prednisone and I’m afraid to use it. I am afraid that it will cause serious problems for my baby. How can I manage autoimmune hemolytic anemia better in terms of diet? I really want my baby to be healthy. Hematologist: If even hemolysis cannot be controlled, anemia will have a greater impact on fetal development and may even cause miscarriage or fetal death in the womb. The most effective drug for the treatment of autoimmune hemolytic anemia and the one with the least impact on the fetus is prednisone, and its use after the third month of pregnancy has a small chance of causing fetal malformation. Diet is not effective for autoimmune hemolytic anemia. The key to treatment is to control the destruction of red blood cells by autoantibodies. Patient: Dr. Liu, I went to check my hemoglobin again in a few days and it dropped to 61g again, I really don’t know what to do, I’m really worried about the baby in my belly, I hope I can get your help! Hematologist: Hormones must be used in order to control autoimmune hemolytic anemia, and there is not much effect on the fetus.