Hepatitis B antibody is a specific antibody produced by the hepatitis B virus when the liver cells are attacked by the virus. When after antiviral treatment or the body produces immune clearance against the hepatitis virus, the e antigen titer gradually decreases or disappears and e antibodies appear. e antibodies generally indicate that hepatitis B virus replication is weakened and infectiousness is reduced. e antibody positive clinical significance should be analyzed in conjunction with the five hepatitis B serological tests, as follows: 1. accompanied by hepatitis B virus core antibody positive, suggesting that the hepatitis B virus surface The antibodies appear before the stage of low or no hepatitis B virus replication, which means that most of the hepatitis B virus is eliminated and the infectiousness is reduced, but it is not that no transmission will occur. If the surface antibody of hepatitis B virus is positive, it is the recovery stage of hepatitis B virus infection, and the body has acquired immunity; 2, accompanied by positive surface antigen of hepatitis B virus and positive core antibody of hepatitis B virus, generally known as small triplet, suggesting acute and chronic hepatitis B virus infection, low or no replication of hepatitis B virus, indicating that virus replication is inhibited and the condition is improving, but still infectious; 3, if small triplet is also If hepatitis B virus DNA is detected at the same time, it indicates hepatitis B virus e antigen negative chronic hepatitis B with more active viral replication, which is accompanied by chronic active inflammation of the liver and fluctuating serum ghrelin levels, which should be taken seriously and timely medical attention to avoid developing into heavy hepatitis, liver cirrhosis and liver cancer. For small triplets with symptoms of hepatitis attacks, treatment is based on antiviral drugs, such as interferon, nucleoside analogues, and anti-inflammatory and liver-protective drugs. The pathogenesis of hepatitis B is complex and cannot be inferred by a single indicator. If symptoms such as weakness, anorexia, deepening of urine color, or pain in the liver area are found, prompt medical attention should be sought.