The statement of thyroid nodule nemesis is unscientific. Thyroid nodules have different causes and different treatments. Most of the thyroid nodules are found through physical examination. After the discovery of thyroid nodules, it is necessary to assess the nature and function of the thyroid nodules through ultrasonography, thyroid-related swelling markers, and thyroid function tests. If the thyroid nodule is non-functional and benign, and the nodule is small and has no compression symptoms, it can be left untreated for the time being, and regular checkups will be sufficient; if the nodule is large and has compression symptoms, surgery will be required. If the thyroid nodule is functional and causes hyperthyroidism, anti-thyroid medication, radioactive iodine therapy or surgery should be chosen according to the patient’s specific condition. If the thyroid nodule is suspected to be malignant, puncture biopsy can be perfected and timely surgical treatment. When a patient is diagnosed with thyroid nodules, he or she should immediately go to the hospital and have a specialized doctor decide on the next step of treatment.