Normally, the spleen does not return to its normal size unless it is enlarged in the short term as a result of hemolytic anemia.
Hemolytic anemia is a type of anemia that has many causes, such as chemical exposure, heredity, and infection. In hemolytic anemia, red blood cells are destroyed excessively for various reasons, resulting in anemia due to insufficient hemoglobin in the patient’s body.
The destruction of blood cells in hemolytic anemia can occur either intravascularly or extravascularly. In the former case, such as blood transfusion with incompatible blood groups and paroxysmal sleep hemoglobinuria, the spleen itself will not increase in size; in the latter case, such as hereditary spherocytosis, the red blood cells are destroyed in the spleen, which will reactively enlarge due to bruising, and it will be more difficult to return to the normal size of the spleen.
It is very rare for the spleen to shrink, mainly when the cause of hemolytic anemia can be removed in a short period of time.
When hemolytic anemia causes splenomegaly, it is necessary to actively consult the doctor and follow the doctor’s instructions for reasonable treatment.